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Noun(1) therapy that uses a local electric current to introduce the ions of a medicine into the tissues

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(1) Other delivery vehicles for topical anesthesia currently in development, including iontophoresis and anesthetic patches, may one day give patients and physicians even more flexibility.(2) If symptoms are not relieved, physical therapy that includes ultrasonography, massage, and iontophoresis should be considered.(3) During sweat stimulation, a variety of chemicals are used at the negative electrode to complete the circuit during iontophoresis .(4) A process called iontophoresis applies electricity to the affected area.(5) Magnetic insoles have no demonstrated benefit, nor does therapeutic ultrasonography, laser therapy, iontophoresis , or electron-generating devices.(6) When picrotoxin was applied iontophoretically during peripheral nerve stimulation, the analgesic effect was reduced.(7) The membrane potential responses and firing patterns of rat thalamic neurons evoked by iontophoretically applied excitatory amino acids were recorded in vivo.(8) Porcine skin has been extensively studied and validated as an excellent model of the human membrane with respect to iontophoretic drug delivery.(9) There is little information available on the feasibility of transdermal iontophoretic delivery of anticancer agents in vivo.(10) Reduced sweating was observed after iontophoretically applied acetylcholine on the forearm.(11) The primary transdermal iontophoretic route seems to be appendageal or intercellular through pre-existing pathways or as a result of low(12) The problem of too rapid drug clearance from the viable skin compartment has been addressed in iontophoretic drug development.(13) This invention relates to novel methods and devices for iontophoretically administering therapeutic doses of cell adhesion receptor antagonists in a controlled manner through the skin.(14) The reverse iontophoretic extraction of glucose across the skin is primarily electroosmotic and has been successfully used to monitor glycemia in diabetics.(15) The dye was iontophoretically injected by current pulses of short duration, generated by the electrometer.
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